Sonoda T, Nagata Y, Mori M, et al. A case-control study of diet and prostate cancer in Japan: possible protective effect of traditional Japanese diet. Cancer Sci 2004;95:238-42. . View abstract.
Srichairatanakool S, Ounjaijean S, Thephinlap C, Khansuwan U, Phisalpong C, Fucharoen S. Iron-chelating and free-radical scavenging activities of microwave-processed green tea in iron overload. Hemoglobin. 2006;30(2):311-27. View abstract.
Staib, A. H., Stille, W., Dietlein, G., Shah, P. M., Harder, S., Mieke, S., and Beer, C. Interaction between quinolones and caffeine. Drugs 1987;34 Suppl 1:170-174. View abstract.
Stammler G, Volm M. Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines. Anticancer Drugs 1997;8:265-8. View abstract.
Stanek EJ, Melko GP, Charland SL. Xanthine interference with dipyridamole-thallium-201 myocardial imaging. Pharmacother 1995;29:425-7. View abstract.
Starbuck JM, Llambrich S, Gonzàlez R, et al. Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome. Sci Rep 2021;11(1):4715. View abstract.
Stille, W., Harder, S., Mieke, S., Beer, C., Shah, P. M., Frech, K., and Staib, A. H. Decrease of caffeine elimination in man during co-administration of 4-quinolones. J.Antimicrob.Chemother. 1987;20(5):729-734. View abstract.
Stookey JD. The diuretic effects of alcohol and caffeine and total water intake misclassification. Eur J Epidemiol 1999;15:181-8. View abstract.
Sun J. Morning/evening menopausal formula relieves menopausal symptoms: a pilot study. J Altern Complement Med 2003;9:403-9. View abstract.
Suzuki S, Murayama Y, Sugiyama E, et al. Estimating pediatric doses of drugs metabolized by cytochrome P450 (CYP) isozymes, based on physiological liver development and serum protein levels. Yakugaku Zasshi 2010;130:613-20. View abstract.
Suzuki Y, Tsubono Y, Nakaya N, et al. Green tea and the risk of breast cancer: pooled analysis of two prospective studies in Japan. Br J Cancer 2004;90:1361-3. View abstract.
Tajima K, Tominaga S. Dietary habits and gastro-intestinal cancers: a comparative case-control study of stomach and large intestinal cancers in Nagoya, Japan. Jpn J Cancer Res 1985;76:705-16.. View abstract.
Takada M, Yamagishi K, Iso H, Tamakoshi A. Green tea consumption and risk of hematologic neoplasms: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study). Cancer Causes Control. 2019;30(11):1223-1230. View abstract.
Takahashi M, Ozaki M, Miyashita M, et al. Effects of timing of acute catechin-rich green tea ingestion on postprandial glucose metabolism in healthy men. J Nutr Biochem. 2019;73:108221. View abstract.
Taubert D, Roesen R, Schomig E. Effect of cocoa and tea intake on blood pressure: a meta-analysis. Arch Intern Med 2007;167:626-34. View abstract.
Taylor JR, Wilt VM. Probable antagonism of warfarin by green tea. Ann Pharmacother 1999;33:426-8. View abstract.
Temme EH, Van Hoydonck PG. Tea consumption and iron status. Eur J Clin Nutr 2002;56:379-86.. View abstract.
Teramoto M, Muraki I, Yamagishi K, Tamakoshi A, Iso H. Green tea and coffee consumption and all-cause mortality among persons with and without stroke or myocardial infarction. Stroke 2021;52(3):957-965. View abstract.
Teramoto M, Yamagishi K, Muraki I, Tamakoshi A, Iso H. Coffee and green tea consumption and cardiovascular disease mortality among people with and without hypertension. J Am Heart Assoc 2023;12(2):e026477. View abstract.
The National Toxicology Program (NTP). Caffeine. Center for the Evaluation of Risks to Human Reproduction (CERHR). Available at: https://cerhr.niehs.nih.gov/common/caffeine.html.
Toolsee NA, Aruoma OI, Gunness TK, Kowlessur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Rondeau P, Bourdon E, Bahorun T. Effectiveness of green tea in a randomized human cohort: relevance to diabetes and its complications. Biomed Res Int. 2013;2013:412379. View abstract.
Trudel D, Labbé DP, Araya-Farias M, Doyen A, Bazinet L, Duchesne T, Plante M, Grégoire J, Renaud MC, Bachvarov D, Têtu B, Bairati I. A two-stage, single-arm, phase II study of EGCG-enriched green tea drink as a maintenance therapy in women with advanced stage ovarian cancer. Gynecol Oncol. 2013 Nov;131(2):357-61. View abstract.
Tsubono Y, Nishino Y, Komatsu S, et al. Green tea and the risk of gastric cancer in Japan. N Engl J Med 2001;344:632-6. View abstract.
Turpault S, Brian W, Van Horn R, et al. Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6, and 3A. Br J Clin Pharmacol 2009;68:928-35. View abstract.
Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. View abstract.
Ursing, C., Wikner, J., Brismar, K., and Rojdmark, S. Caffeine raises the serum melatonin level in healthy subjects: an indication of melatonin metabolism by cytochrome P450(CYP)1A2. J.Endocrinol.Invest 2003;26(5):403-406. View abstract.
Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3. View abstract.
van der Hoeven N, Visser I, Schene A, van den Born BJ. Severe hypertension related to caffeinated coffee and tranylcypromine: a case report. Ann Intern Med. 2014 May 6;160(9):657-8. doi: 10.7326/L14-5009-8. No abstract available. View abstract.
Vandeberghe K, Gillis N, Van Leemputte M, et al. Caffeine counteracts the ergogenic action of muscle creatine loading. J Appl Physiol 1996;80:452-7. View abstract.
Vaz, J., Kulkarni, C., David, J., and Joseph, T. Influence of caffeine on pharmacokinetic profile of sodium valproate and carbamazepine in normal human volunteers. Indian J.Exp.Biol. 1998;36(1):112-114. View abstract.
Veerman GDM, van der Werff SC, Koolen SLW, et al. The influence of green tea extract on nintedanib's bioavailability in patients with pulmonary fibrosis. Biomed Pharmacother 2022;151:113101. View abstract.
Vilela MM, Salvador SL, Teixeira IGL, Del Arco MCG, De Rossi A. Efficacy of green tea and its extract, epigallocatechin-3-gallate, in the reduction of cariogenic microbiota in children: a randomized clinical trial. Arch Oral Biol. 2020;114:104727. View abstract.
Vinson JA, Teufel K, Wu N. Green and black teas inhibit atherosclerosis by lipid, antioxidant, and fibrinolytic mechanisms. J Agric Food Chem 2004;52:3661-5. View abstract.
Voskoboinik A, Kalman JM, Kistler PM. Caffeine and arrhythmias: time to grind the data. JACC: Clin Electrophysiol. 2018;4(4):425-32.
Wahllander A, Paumgartner G. Effect of ketoconazole and terbinafine on the pharmacokinetics of caffeine in healthy volunteers. Eur J Clin Pharmacol 1989;37:279-83. View abstract.
Wakabayashi K, Kono S, Shinchi K, et al. Habitual coffee consumption and blood pressure: A study of self-defense officials in Japan. Eur J Epidemiol 1998;14:669-73. View abstract.
Wakai K, Ohno Y, Obata K. Prognostic significance of selected lifestyle factors in urinary bladder cancer. Jpn J Cancer Res 1993;84:1223-9. View abstract.
Wallach J. Interpretation of Diagnostic Tests. A synopsis of Laboratory Medicine. Fifth ed; Boston, MA: Little Brown, 1992.
Wang S, Li X, Yang Y, et al. Does coffee, tea and caffeine consumption reduce the risk of incident breast cancer? A systematic review and network meta-analysis. Public Health Nutr 2021;24(18):6377-6389. View abstract.
Wang W, Yang Y, Zhang W, Wu W. Association of tea consumption and the risk of oral cancer: a meta-analysis. Oral Oncol. 2014 Apr;50(4):276-81. View abstract.
Wang X, Lin YW, Wang S, Wu J, Mao QQ, Zheng XY, Xie LP. A meta-analysis of tea consumption and the risk of bladder cancer. Urol Int. 2013;90(1):10-6. View abstract.
Wang XJ, Zeng XT, Duan XL, Zeng HC, Shen R, Zhou P. Association between green tea and colorectal cancer risk: a meta-analysis of 13 case-control studies. Asian Pac J Cancer Prev. 2012;13(7):3123-7. View abstract.
Wang Y, Yu X, Wu Y, Zhang D. Coffee and tea consumption and risk of lung cancer: a dose-response analysis of observational studies. Lung Cancer. 2012;78(2):169-70. View abstract.
Wang YC, Huang TL. Anti-Helicobacter pylori activity of Plumbago zeylanica L. FEMS Immunol Med Microbiol. 2005 Mar 1;43(3):407-12. View abstract.
Wang ZH, Gao QY, Fang JY. Green tea and incidence of colorectal cancer: evidence from prospective cohort studies. Nutr Cancer. 2012;64(8):1143-52. View abstract.
Wang ZM, Zhao D, Wang H, Wang QM, Zhou B, Wang LS. Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies. Nutr Metab Cardiovasc Dis 2023;33(4):715-723. View abstract.
Wang, X. and Yeung, J. H. Effects of the aqueous extract from Salvia miltiorrhiza Bunge on caffeine pharmacokinetics and liver microsomal CYP1A2 activity in humans and rats. J Pharm Pharmacol 2010;62(8):1077-1083. View abstract.
Watson JM, Jenkins EJ, Hamilton P, et al. Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes. Diabetes Care 2000;23:455-9. View abstract.
Watson JM, Sherwin RS, Deary IJ, et al. Dissociation of augmented physiological, hormonal and cognitive responses to hypoglycaemia with sustained caffeine use. Clin Sci (Lond) 2003;104:447-54. View abstract.
Weisburger JH. Tea and health: the underlying mechanisms. Proc Soc Exp Biol Med 1999;220:271-5. View abstract.
Wemple RD, Lamb DR, McKeever KH. Caffeine vs caffeine-free sports drinks: effects on urine production at rest and during prolonged exercise. Int J Sports Med 1997;18:40-6. View abstract.
Weng X, Odouli R, Li DK. Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. Am J Obstet Gynecol 2008;198:279.e1-8. View abstract.
Wikoff D, Welsh BT, Henderson R, et al. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol 2017;109:585-648. View abstract.
Williams MH, Branch JD. Creatine supplementation and exercise performance: an update. J Am Coll Nutr 1998;17:216-34. View abstract.
Winkelmayer WC, Stampfer MJ, Willett WC, Curhan GC. Habitual caffeine intake and the risk of hypertension in women. JAMA 2005;294:2330-5. View abstract.
Wojcikowski, J. and Daniel, W. A. Perazine at therapeutic drug concentrations inhibits human cytochrome P450 isoenzyme 1A2 (CYP1A2) and caffeine metabolism--an in vitro study. Pharmacol Rep. 2009;61(5):851-858. View abstract.
Wu AH, Tseng CC, Van Den Berg D, Yu MC. Tea intake, COMT genotype, and breast cancer in Asian-American women. Cancer Res 2003;63:7526-9. View abstract.
Wu AH, Yu MC, Tseng CC, et al. Green tea and risk of breast cancer in Asian Americans. Int J Cancer 2003;106:574-9. View abstract.
Wu CH, Yang YC, Yao WJ, et al. Epidemiological evidence of increased bone mineral density in habitual tea drinkers. Arch Intern Med 2002;162:1001-6. View abstract.
Xie L, Tang Q, Yao D, et al. Effect of decaffeinated green tea polyphenols on body fat and precocious puberty in obese girls: A randomized controlled trial. Front Endocrinol (Lausanne) 2021;12:736724. View abstract.
Xu R, Yang K, Ding J, Chen G. Effect of green tea supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore). 2020;99(6):e19047. View abstract.
Yaegashi A, Kimura T, Hirata T, Tamakoshi A. Green tea consumption and risk of depression symptoms: A systematic review and meta-analysis of observational studies. J Nutr Sci Vitaminol (Tokyo) 2022;68(3):155-161. View abstract.
Yanagida A, Shoji A, Shibusawa Y, et al. Analytical separation of tea catechins and food-related polyphenols by high-speed counter-current chromatography. J Chromatogr A 2006;1112:195-201. View abstract.
Yang YC, Lu FH, Wu JS, et al. The protective effect of habitual tea consumption on hypertension. Arch Intern Med 2004 26;164:1534-40. View abstract.
Yates AA, Erdman JW Jr, Shao A, Dolan LC, Griffiths JC. Bioactive nutrients - Time for tolerable upper intake levels to address safety. Regul Toxicol Pharmacol. 2017;84:94-101. View abstract.
Yi Y, Liang H, Jing H, et al. Green Tea Consumption and Esophageal Cancer Risk: A Meta-analysis. Nutr Cancer. 2019 Jul 5:1-9. View abstract.
Yildirim Ayaz E, Dincer B, Mesci B. Effect of green tea on blood pressure in healthy individuals: A meta-analysis. Altern Ther Health Med 2023;29(5):66-73. View abstract.
Younes M, Aggett P, Aguilar F, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS). Scientific opinion on the safety of green tea catechins. EFSA Journal 2018;16(4):5239.
Yu F, Jin Z, Jiang H, Xiang C, Tang J, Li T, He J. Tea consumption and the risk of five major cancers: a dose-response meta-analysis of prospective studies. BMC Cancer. 2014 Mar 17;14:197. View abstract.
Yu GP, Hsieh CC. Risk factors for stomach cancer: a population-based case-control study in Shanghai. Cancer Causes Control 1991;2:169-74.. View abstract.
Yu J, Liang D, Li J, et al. Coffee, green tea intake, and the risk of hepatocellular carcinoma: A systematic review and meta-analysis of observational studies. Nutr Cancer 2023;75(5):1295-1308. View abstract.
Yuan JM, Koh WP, Sun CL, et al. Green tea intake, ACE gene polymorphism and breast cancer risk among Chinese women in Singapore. Carcinogenesis 2005;26:1389-94. View abstract.
Zelicha H, Kloting N, Kaplan A, et al. The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial. BMC Med 2022;20(1):327. View abstract.
Zhang M, Binns CW, Lee AH. Tea consumption and ovarian cancer risk: a case-control study in China. Cancer Epidemiol Biomarkers Prev 2002;11:713-8.. View abstract.
Zhang M, Zhao X, Zhang X, Holman CD. Possible protective effect of green tea intake on risk of adult leukaemia. Br J Cancer. 2008 Jan 15;98(1):168-70. View abstract.
Zhang Q, Wei D, Liu J. In vivo reversal of doxorubicin resistance by (-)-epigallocatechin gallate in a solid human carcinoma xenograft. Cancer Lett. 2004 May 28;208(2):179-86. View abstract.
Zhang T, Li N, Chen SI, Hou Z, Saito A. Effects of green tea extract combined with brisk walking on lipid profiles and the liver function in overweight and obese men: A randomized, double-blinded, placebo-control trial. An Acad Bras Cienc. 2020;92(4):e20191594. View abstract.
Zhang X, Zhang R, Chen D, et al. Association of tea drinking and dysmenorrhoea among reproductive-age women in Shanghai, China (2013-2015): a cross-sectional study. BMJ Open. 2019;9(4):e026643. View abstract.
Zhang Y, Yang H, Li S, Li WD, Wang Y. Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank. PLoS Med 2021;18(11):e1003830. View abstract.
Zhang, Y. et al., Effects of catechin-enriched green tea beverage on visceral fat loss in adults with a high pro-portion of visceral fat: A double-blind, placebo-controlled, randomized trial, Journal of Functional Foods (2012), doi:10.1016/j.jff.2011.12.010
Zhao H, Mei K, Yang L, Liu X, Xie L. Green tea consumption and risk for esophageal cancer: A systematic review and dose-response meta-analysis. Nutrition 2021;87-88:111197. View abstract.
Zhao H, Zhu W, Zhao X, et al. Efficacy of epigallocatechin-3-gallate in preventing dermatitis in patients with breast cancer receiving postoperative radiotherapy: A double-blind, placebo-controlled, phase 2 randomized clinical trial. JAMA Dermatol 2022;158(7):779-786. View abstract.
Zheng G, Sayama K, Okubo T, et al. Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo 2004;18:55-62. View abstract.
Zheng JS, Yang J, Fu YQ, Huang T, Huang YJ, Li D. Effects of green tea, black tea, and coffee consumption on the risk of esophageal cancer: a systematic review and meta-analysis of observational studies. Nutr Cancer. 2013;65(1):1-16. View abstract.
Zheng KH, Zhu K, Wactawski-Wende J, et al. Caffeine intake from coffee and tea and invasive breast cancer incidence among postmenopausal women in the Women's Health Initiative. Int J Cancer 2021;149(12):2032-2044. View abstract.
Abdel Halim, A. S. Efficacy of Zingiber officinale on third stage larvae and adult fecundity of Musca domestica and Anopheles pharoensis. J Egypt Soc.Parasitol. 2008;38(2):385-392. View abstract.
Abdel-Aziz, H., Nahrstedt, A., Petereit, F., Windeck, T., Ploch, M., and Verspohl, E. J. 5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale. Planta Med 2005;71(7):609-616. View abstract.
Abdel-Aziz, H., Windeck, T., Ploch, M., and Verspohl, E. J. Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum. Eur.J Pharmacol. 1-13-2006;530(1-2):136-143. View abstract.
Ahui, M. L., Champy, P., Ramadan, A., Pham, Van L., Araujo, L., Brou, Andre K., Diem, S., Damotte, D., Kati-Coulibaly, S., Offoumou, M. A., Dy, M., Thieblemont, N., and Herbelin, A. Ginger prevents Th2-mediated immune responses in a mouse model of airway inflammation. Int Immunopharmacol. 12-10-2008;8(12):1626-1632. View abstract.
Aktan, F., Henness, S., Tran, V. H., Duke, C. C., Roufogalis, B. D., and Ammit, A. J. Gingerol metabolite and a synthetic analogue Capsarol inhibit macrophage NF-kappaB-mediated iNOS gene expression and enzyme activity. Planta Med 2006;72(8):727-734. View abstract.
al Yahya, M. A., Rafatullah, S., Mossa, J. S., Ageel, A. M., Parmar, N. S., and Tariq, M. Gastroprotective activity of ginger zingiber officinale rosc., in albino rats. Am.J Chin Med. 1989;17(1-2):51-56. View abstract.
Alzoreky, N. S. and Nakahara, K. Antibacterial activity of extracts from some edible plants commonly consumed in Asia. Int J Food Microbiol. 2-15-2003;80(3):223-230. View abstract.
Ansari, M. N., Bhandari, U., and Pillai, K. K. Ethanolic Zingiber officinale R. extract pretreatment alleviates isoproterenol-induced oxidative myocardial necrosis in rats. Indian J Exp.Biol. 2006;44(11):892-897. View abstract.
Asnani, V. and Verma, R. J. Antioxidative effect of rhizome of Zinziber officinale on paraben induced lipid peroxidation: an in vitro study. Acta Pol.Pharm. 2007;64(1):35-37. View abstract.
Asnani, V. M. and Verma, R. J. Ameliorative effects of ginger extract on paraben-induced lipid peroxidation in the liver of mice. Acta Pol.Pharm. 2009;66(3):225-228. View abstract.
Bhandari, U., Sharma, J. N., and Zafar, R. The protective action of ethanolic ginger (Zingiber officinale) extract in cholesterol fed rabbits. J Ethnopharmacol. 1998;61(2):167-171. View abstract.
Chung, S. W., Kim, M. K., Chung, J. H., Kim, D. H., Choi, J. S., Anton, S., Seo, A. Y., Park, K. Y., Yokozawa, T., Rhee, S. H., Yu, B. P., and Chung, H. Y. Peroxisome proliferator-activated receptor activation by a short-term feeding of zingerone in aged rats. J Med Food 2009;12(2):345-350. View abstract.
Cwikla, C., Schmidt, K., Matthias, A., Bone, K. M., Lehmann, R., and Tiralongo, E. Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni. Phytother.Res 2010;24(5):649-656. View abstract.
Dugasani, S., Pichika, M. R., Nadarajah, V. D., Balijepalli, M. K., Tandra, S., and Korlakunta, J. N. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J.Ethnopharmacol. 2-3-2010;127(2):515-520. View abstract.
El Abhar, H. S., Hammad, L. N., and Gawad, H. S. Modulating effect of ginger extract on rats with ulcerative colitis. J Ethnopharmacol. 8-13-2008;118(3):367-372. View abstract.
Ficker, C. E., Arnason, J. T., Vindas, P. S., Alvarez, L. P., Akpagana, K., Gbeassor, M., De Souza, C., and Smith, M. L. Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts. Mycoses 2003;46(1-2):29-37. View abstract.
Ficker, C., Smith, M. L., Akpagana, K., Gbeassor, M., Zhang, J., Durst, T., Assabgui, R., and Arnason, J. T. Bioassay-guided isolation and identification of antifungal compounds from ginger. Phytother.Res. 2003;17(8):897-902. View abstract.
Fouda, A. M. and Berika, M. Y. Evaluation of the effect of hydroalcoholic extract of Zingiber officinale rhizomes in rat collagen-induced arthritis. Basic Clin Pharmacol.Toxicol. 2009;104(3):262-271. View abstract.
Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290. View abstract.
Ghayur, M. N. and Gilani, A. H. Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders. Dig.Dis.Sci 2005;50(10):1889-1897. View abstract.
Ghayur, M. N., Gilani, A. H., Afridi, M. B., and Houghton, P. J. Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul.Pharmacol. 2005;43(4):234-241. View abstract.
Ghayur, M. N., Gilani, A. H., and Janssen, L. J. Ginger attenuates acetylcholine-induced contraction and Ca2+ signalling in murine airway smooth muscle cells. Can J Physiol Pharmacol. 2008;86(5):264-271. View abstract.
Guh, J. H., Ko, F. N., Jong, T. T., and Teng, C. M. Antiplatelet effect of gingerol isolated from Zingiber officinale. J Pharm.Pharmacol. 1995;47(4):329-332. View abstract.
Gupta, Y. K. and Sharma, M. Reversal of pyrogallol-induced delay in gastric emptying in rats by ginger (Zingiber officinale). Methods Find.Exp.Clin Pharmacol. 2001;23(9):501-503. View abstract.
Habib, S. H., Makpol, S., Abdul, Hamid NA, Das, S., Ngah, W. Z., and Yusof, Y. A. Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. Clinics.(Sao Paulo) 2008;63(6):807-813. View abstract.
Han, L. K., Morimoto, C., Zheng, Y. N., Li, W., Asami, E., Okuda, H., and Saito, M. [Effects of zingerone on fat storage in ovariectomized rats]. Yakugaku Zasshi 2008;128(8):1195-1201. View abstract.
Henning, S. M., Zhang, Y., Seeram, N. P., Lee, R. P., Wang, P., Bowerman, S., and Heber, D. Antioxidant capacity and phytochemical content of herbs and spices in dry, fresh and blended herb paste form. Int J Food Sci Nutr 2011;62(3):219-225. View abstract.
Horie, S., Yamamoto, H., Michael, G. J., Uchida, M., Belai, A., Watanabe, K., Priestley, J. V., and Murayama, T. Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats. Scand.J Gastroenterol. 2004;39(4):303-312. View abstract.
Ippoushi, K., Azuma, K., Ito, H., Horie, H., and Higashio, H. [6]-Gingerol inhibits nitric oxide synthesis in activated J774.1 mouse macrophages and prevents peroxynitrite-induced oxidation and nitration reactions. Life Sci 11-14-2003;73(26):3427-3437. View abstract.
Ippoushi, K., Ito, H., Horie, H., and Azuma, K. Mechanism of inhibition of peroxynitrite-induced oxidation and nitration by [6]-gingerol. Planta Med 2005;71(6):563-566. View abstract.
Iqbal, Z., Lateef, M., Akhtar, M. S., Ghayur, M. N., and Gilani, A. H. In vivo anthelmintic activity of ginger against gastrointestinal nematodes of sheep. J Ethnopharmacol. 6-30-2006;106(2):285-287. View abstract.
Janssen, P. L., Meyboom, S., van Staveren, W. A., de Vegt, F., and Katan, M. B. Consumption of ginger (Zingiber officinale roscoe) does not affect ex vivo platelet thromboxane production in humans. Eur.J Clin Nutr. 1996;50(11):772-774. View abstract.
Jolad, S. D., Lantz, R. C., Solyom, A. M., Chen, G. J., Bates, R. B., and Timmermann, B. N. Fresh organically grown ginger (Zingiber officinale): composition and effects on LPS-induced PGE2 production. Phytochemistry 2004;65(13):1937-1954. View abstract.
Jung, H. W., Yoon, C. H., Park, K. M., Han, H. S., and Park, Y. K. Hexane fraction of Zingiberis Rhizoma Crudus extract inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated BV2 microglial cells via the NF-kappaB pathway. Food Chem.Toxicol. 2009;47(6):1190-1197. View abstract.
Kadnur, S. V. and Goyal, R. K. Beneficial effects of Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats. Indian J Exp.Biol. 2005;43(12):1161-1164. View abstract.
Kamtchouing, P., Mbongue Fandio, G. Y., Dimo, T., and Jatsa, H. B. Evaluation of androgenic activity of Zingiber officinale and Pentadiplandra brazzeana in male rats. Asian J Androl 2002;4(4):299-301. View abstract.
Kim, H. W., Murakami, A., Abe, M., Ozawa, Y., Morimitsu, Y., Williams, M. V., and Ohigashi, H. Suppressive effects of mioga ginger and ginger constituents on reactive oxygen and nitrogen species generation, and the expression of inducible pro-inflammatory genes in macrophages. Antioxid.Redox.Signal. 2005;7(11-12):1621-1629. View abstract.
Lantz, R. C., Chen, G. J., Sarihan, M., Solyom, A. M., Jolad, S. D., and Timmermann, B. N. The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine 2007;14(2-3):123-128. View abstract.
Lee, T. Y., Lee, K. C., Chen, S. Y., and Chang, H. H. 6-Gingerol inhibits ROS and iNOS through the suppression of PKC-alpha and NF-kappaB pathways in lipopolysaccharide-stimulated mouse macrophages. Biochem.Biophys.Res Commun. 4-24-2009;382(1):134-139. View abstract.
Liu, N., Huo, G., Zhang, L., and Zhang, X. [Effect of Zingiber OfficinaleRosc on lipid peroxidation in hyperlipidemia rats]. Wei Sheng Yan.Jiu. 2003;32(1):22-23. View abstract.
Liu, P. H. and Ho, H. L. Ginger and drug bezoar induced small bowel obstruction. J R.Coll.Surg.Edinb. 1983;28(6):397-398. View abstract.
Lohsiriwat, S., Rukkiat, M., Chaikomin, R., and Leelakusolvong, S. Effect of ginger on lower esophageal sphincter pressure. J.Med.Assoc.Thai. 2010;93(3):366-372. View abstract.
Lumb, A. B. Effect of dried ginger on human platelet function. Thromb.Haemost. 1994;71(1):110-111. View abstract.
Mahady, G. B., Pendland, S. L., Stoia, A., Hamill, F. A., Fabricant, D., Dietz, B. M., and Chadwick, L. R. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother.Res 2005;19(11):988-991. View abstract.
Mansour, M. S., Ni, Y. M., Roberts, A. L., Kelleman, M., Roychoudhury, A., and St-Onge, M. P. Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: a pilot study. Metabolism 2012;61(10):1347-1352. View abstract.
Onogi, T., Minami, M., Kuraishi, Y., and Satoh, M. Capsaicin-like effect of (6)-shogaol on substance P-containing primary afferents of rats: a possible mechanism of its analgesic action. Neuropharmacology 1992;31(11):1165-1169. View abstract.
Onyenekwe, P. C. Assessment of oleoresin and gingerol contents in gamma irradiated ginger rhizomes. Nahrung 2000;44(2):130-132. View abstract.
Park, M., Bae, J., and Lee, D. S. Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria. Phytother.Res 2008;22(11):1446-1449. View abstract.
Phan, P. V., Sohrabi, A., Polotsky, A., Hungerford, D. S., Lindmark, L., and Frondoza, C. G. Ginger extract components suppress induction of chemokine expression in human synoviocytes. J Altern.Complement Med 2005;11(1):149-154. View abstract.
Pozzatti, P., Scheid, L. A., Spader, T. B., Atayde, M. L., Santurio, J. M., and Alves, S. H. In vitro activity of essential oils extracted from plants used as spices against fluconazole-resistant and fluconazole-susceptible Candida spp. Can J Microbiol. 2008;54(11):950-956. View abstract.
Prajapati, V., Tripathi, A. K., Aggarwal, K. K., and Khanuja, S. P. Insecticidal, repellent and oviposition-deterrent activity of selected essential oils against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus. Bioresour.Technol. 2005;96(16):1749-1757. View abstract.
Pushpanathan, T., Jebanesan, A., and Govindarajan, M. The essential oil of Zingiber officinalis Linn (Zingiberaceae) as a mosquito larvicidal and repellent agent against the filarial vector Culex quinquefasciatus Say (Diptera: Culicidae). Parasitol.Res 2008;102(6):1289-1291. View abstract.
Qian, Q. H., Yue, W., Wang, Y. X., Yang, Z. H., Liu, Z. T., and Chen, W. H. Gingerol inhibits cisplatin-induced vomiting by down regulating 5-hydroxytryptamine, dopamine and substance P expression in minks. Arch Pharm.Res 2009;32(4):565-573. View abstract.
Rahuman, A. A., Gopalakrishnan, G., Venkatesan, P., Geetha, K., and Bagavan, A. Mosquito larvicidal activity of isolated compounds from the rhizome of Zingiber officinale. Phytother.Res 2008;22(8):1035-1039. View abstract.
Sambaiah, K. and Srinivasan, K. Effect of cumin, cinnamon, ginger, mustard and tamarind in induced hypercholesterolemic rats. Nahrung 1991;35(1):47-51. View abstract.
Schwertner, H. A., Rios, D. C., and Pascoe, J. E. Variation in concentration and labeling of ginger root dietary supplements. Obstet.Gynecol. 2006;107(6):1337-1343. View abstract.
Sekiya, K., Ohtani, A., and Kusano, S. Enhancement of insulin sensitivity in adipocytes by ginger. Biofactors 2004;22(1-4):153-156. View abstract.
Sharma, S. S. and Gupta, Y. K. Reversal of cisplatin-induced delay in gastric emptying in rats by ginger (Zingiber officinale). J Ethnopharmacol. 1998;62(1):49-55. View abstract.
Shen, C. L., Hong, K. J., and Kim, S. W. Effects of ginger (Zingiber officinale Rosc.) on decreasing the production of inflammatory mediators in sow osteoarthrotic cartilage explants. J Med Food 2003;6(4):323-328. View abstract.
Shin, S. G., Kim, J. Y., Chung, H. Y., and Jeong, J. C. Zingerone as an antioxidant against peroxynitrite. J Agric.Food Chem. 9-21-2005;53(19):7617-7622. View abstract.
Sripramote, M. and Lekhyananda, N. A randomized comparison of ginger and vitamin B6 in the treatment of nausea and vomiting of pregnancy. J Med Assoc.Thai. 2003;86(9):846-853. View abstract.
Srivastava, K. C. Isolation and effects of some ginger components on platelet aggregation and eicosanoid biosynthesis. Prostaglandins Leukot.Med. 1986;25(2-3):187-198. View abstract.
Tao, Q. F., Xu, Y., Lam, R. Y., Schneider, B., Dou, H., Leung, P. S., Shi, S. Y., Zhou, C. X., Yang, L. X., Zhang, R. P., Xiao, Y. C., Wu, X., Stockigt, J., Zeng, S., Cheng, C. H., and Zhao, Y. Diarylheptanoids and a monoterpenoid from the rhizomes of Zingiber officinale: antioxidant and cytoprotective properties. J Nat.Prod. 2008;71(1):12-17. View abstract.
Thongson, C., Davidson, P. M., Mahakarnchanakul, W., and Vibulsresth, P. Antimicrobial effect of Thai spices against Listeria monocytogenes and Salmonella typhimurium DT104. J Food Prot. 2005;68(10):2054-2058. View abstract.
Verma, S. K., Singh, J., Khamesra, R., and Bordia, A. Effect of ginger on platelet aggregation in man. Indian J Med.Res 1993;98:240-242. View abstract.
Wu, C. X., Wei, X. B., Ding, H., Sun, X., and Cheng, X. M. [Protective effect of effective parts of Zingiber Offecinal on vascular endothelium of the experimental hyperlipidemic rats]. Zhong.Yao Cai. 2006;29(8):810-813. View abstract.
Wu, K. L., Rayner, C. K., Chuah, S. K., Changchien, C. S., Lu, S. N., Chiu, Y. C., Chiu, K. W., and Lee, C. M. Effects of ginger on gastric emptying and motility in healthy humans. Eur.J Gastroenterol.Hepatol. 2008;20(5):436-440. View abstract.
Yamahara J, Rong HQ, Iwamoto M, and et al. Active components of ginger exhibiting anti-serotonergic action. Phytotherapy Res 1989;3(2):70-71.
Yamahara, J., Huang, Q. R., Li, Y. H., Xu, L., and Fujimura, H. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem.Pharm.Bull.(Tokyo) 1990;38(2):430-431. View abstract.
Yamahara, J., Mochizuki, M., Rong, H. Q., Matsuda, H., and Fujimura, H. The anti-ulcer effect in rats of ginger constituents. J Ethnopharmacol. 1988;23(2-3):299-304. View abstract.
Yu, Y., Zick, S., Li, X., Zou, P., Wright, B., and Sun, D. Examination of the pharmacokinetics of active ingredients of ginger in humans. AAPS.J. 2011;13(3):417-426. View abstract.
Zhang, G. F., Yang, Z. B., Wang, Y., Yang, W. R., Jiang, S. Z., and Gai, G. S. Effects of ginger root (Zingiber officinale) processed to different particle sizes on growth performance, antioxidant status, and serum metabolites of broiler chickens. Poult.Sci 2009;88(10):2159-2166. View abstract.
Zick, S. M., Djuric, Z., Ruffin, M. T., Litzinger, A. J., Normolle, D. P., Alrawi, S., Feng, M. R., and Brenner, D. E. Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects. Cancer Epidemiol.Biomarkers Prev. 2008;17(8):1930-1936. View abstract.
Zick, S. M., Turgeon, D. K., Vareed, S. K., Ruffin, M. T., Litzinger, A. J., Wright, B. D., Alrawi, S., Normolle, D. P., Djuric, Z., and Brenner, D. E. Phase II study of the effects of ginger root extract on eicosanoids in colon mucosa in people at normal risk for colorectal cancer. Cancer Prev.Res.(Phila) 2011;4(11):1929-1937. View abstract.
Abebe W. Herbal medication: potential for adverse interactions with analgesic drugs. J Clin Pharm Ther. 2002;27:391-401. View abstract.
Adib Rad H, Basirat Z, Bakouei F, et al. Effect of Ginger and Novafen on menstrual pain: A cross-over trial. Taiwan J Obstet Gynecol. 2018 Dec;57(6):806-809. doi: 10.1016/j.tjog.2018.10.006. View abstract.
Aeschbach R, Loliger J, Scott BC. Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol. Food Chem Toxicol 1994;32:31-6. View abstract.
Ahad A, Raish M, Bin Jardan YA, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats. Xenobiotica. 2020:1-11. View abstract.
Akbarzadeh E, Heydari M, Atarzadeh F, Jaladat AM. Chronic dysuria following ginger (Zingiber officinale) use: a case report. Galen Med J 2018;7:e1086. View abstract.
Akhani SP, Vishwakarma SL, Goyal RK. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2004;56:101-5. View abstract.
Al-Amin ZM, Thomson M, Al-Qattan KK, et al. Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. Br J Nutr. 2006;96:660-6. View abstract.
Alam MA, Bin Jardan YA, Alzenaidy B, et al. Effect of Hibiscus sabdariffa and Zingiber officinale on pharmacokinetics and pharmacodynamics of amlodipine. J Pharm Pharmacol 2021;73(9):1151-60. View abstract.
Alizadeh-Navaei R, Roozbeh F, Saravi M, et al. Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial. Saudi Med J. 2008;29:1280-4. View abstract.
Altman RD, Marcussen KC. Effects of ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001;44:2531-38. View abstract.
Ameri A, Farashahinejad M, Davoodian P, et al. The efficacy and safety of ginger (Zingiber officinale) rhizome extract in outpatients with COVID-19: A randomized double-blind placebo-control clinical trial. Medicine (Baltimore) 2024;103(22):e38289. View abstract.
Amorndoljai P, Taneepanichskul S, Niempoog S, Nimmannit U. A Comparative of Ginger Extract in Nanostructure Lipid Carrier (NLC) and 1% Diclofenac Gel for Treatment of Knee Osteoarthritis (OA). J Med Assoc Thai. 2017;100(4):447-56. View abstract.
Amorndoljai P, Taneepanichskul S, Niempoog S, Nimmannit U. Improving of Knee Osteoarthritic Symptom by the Local Application of Ginger Extract Nanoparticles: A Preliminary Report with Short Term Follow-Up. J Med Assoc Thai. 2015;98(9):871-7. View abstract.
Anon. Case problem: presenting conventional and complementary approaches for relieving nausea in a breast cancer patient undergoing chemotherapy. J Am Diet Assoc 2000;100:257-9. View abstract.
Ansari M, Porouhan P, Mohammadianpanah M, et al. Efficacy of ginger in control of chemotherapy induced nausea and vomiting in breast cancer patients receiving doxorubicin-based chemotherapy. Asian Pac J Cancer Prev. 2016;17(8):3877-80. View abstract.
Ansari UAMA, Uddin Q, Husain N, Ahmad T, Fatima SH, Minhajuddin A. Evaluation of the efficacy and safety of a herbal formulation for rheumatoid arthritis - A non-inferiority randomized controlled trial. J Ethnopharmacol. 2024 May 10:325:117833. View abstract.
Apariman S, Ratchanon S, Wiriyasirivej B. Effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy. J Med Assoc Thai. 2006;89:2003-9. View abstract.
Araya-Quintanilla F, Gutierrez-Espinoza H, Munoz-Yanez MJ, Sanchez-Montoya U, Lopez-Jeldes J. Effectiveness of ginger on pain and function in knee osteoarthritis: A PRISMA systematic review and meta-analysis. Pain Physician. 2020;23(2):E151-E161. View abstract.
Arfeen Z, Owen H, Plummer JL, et al. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesth Intensive Care 1995;23:449-52. View abstract.
Argento A, Tiraferri E, Marzaloni M. [Oral anticoagulants and medicinal plants. An emerging interaction]. Ann Ital Med Int. 2000;15:139-43. View abstract.
Arslan M, Ozdemir L. Oral intake of ginger for chemotherapy-induced nausea and vomiting among women with breast cancer. Clin J Oncol Nurs. 2015;19(5):E92-7. View abstract.
Aryaeian N, Mahmoudi M, Shahram F, Poursani S, Jamshidi F, Tavakoli H. The effect of ginger supplementation on IL2, TNFα, and IL1β cytokines gene expression levels in patients with active rheumatoid arthritis: A randomized controlled trial. Med J Islam Repub Iran. 2019;33:154. View abstract.
Aryaeian N, Shahram F, Mahmoudi M, et al. The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active rheumatoid arthritis. Gene 2019;698:179-85. View abstract.
Asghari-Jafarabadi M, Khalili L. The Effect of Ginger (Zingiber officinale) on Improving Blood Lipids and Body Weight; A Systematic Review and Multivariate Meta-analysis of Clinical Trials. Curr Pharm Des 2022. View abstract.
Ashraf H, Heydari M, Shams M, Zarshenas MM, Tavakoli A, Sayadi M. Efficacy of ginger supplementation in relieving persistent hypothyroid symptoms in patients with controlled primary hypothyroidism: a pilot randomized, double-blind, placebo-controlled clinical trial. Evid Based Complement Alternat Med 2022;2022:5456855. View abstract.
Azimi P, Ghiasvand R, Feizi A, et al. Effect of cinnamon, cardamom, saffron and ginger consumption on blood pressure and a marker of endothelial function in patients with type 2 diabetes mellitus: A randomized controlled clinical trial. Blood Press. 2016;25(3):133-40. View abstract.
Backon J. Ginger as an antiemetic: possible side effects due to its thromboxane synthetase activity. Anaesthesia. 1991;46(8):705-6.. View abstract.
Backon J. Ginger in preventing nausea and vomiting of pregnancy; a caveat due to its thromboxane synthetase activity and effect on testosterone binding. Eur J Obstet Gynecol Reprod Biol 1991;42:163-4. View abstract.
Badooei F, Imani E, Hosseini-Teshnizi S, Banar M, Memarzade M. Comparison of the effect of ginger and aloe vera mouthwashes on xerostomia in patients with type 2 diabetes: A clinical trial, triple-blind. Med Oral Patol Oral Cir Bucal 2021;26(4):e408-e413. View abstract.
Baek HI, Shen L, Ha KC, et al. Effectiveness and safety of steamed ginger extract on mild osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial. Food Funct 2024;15(18):9512-9523. View abstract.
Bartels EM, Folmer VN, Bliddal H, et al. Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials. Osteoarthritis Cartilage. 2015;23(1):13-21. View abstract.
Bhandari U, Kanojia R, Pillai KK. Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats. J Ethnopharmacol. 2005;97:227-30. View abstract.
Bhargava R, Chasen M, Elten M, MacDonald N. The effect of ginger (Zingiber officinale Roscoe) in patients with advanced cancer. Support Care Cancer. 2019. View abstract.
Black CD, Herring MP, Hurley DJ, O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain 2010;11:894-903. View abstract.
Black CD, O'Connor PJ. Acute effects of dietary ginger on muscle pain induced by eccentric exercise. Phytother Res 2010;24:1620-6. View abstract.
Black CD, Oconnor PJ. Acute effects of dietary ginger on quadriceps muscle pain during moderate-intensity cycling exercise. Int J Sport Nutr Exerc Metab 2008;18:653-64. View abstract.
Bliddal H, Rosetzsky A, Schlichting P, et al. A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage 2000;8:9-12. View abstract.
Bone ME, Wilkinson DJ, Young JR, et al. Ginger root-a new antiemetic. The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 1990;45:669-71. View abstract.
Boonnop R, Meetam P, Siangjong L, et al. Black ginger extract and its active compound, 5,7-dimethoxyflavone, increase intestinal drug absorption via efflux drug transporter inhibitions. Drug Metab Pharmacokinet. 2023;50:100500. View abstract.
Borrelli F, Capasso R, Aviello G, et al. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol 2005;105:849-56. View abstract.
Bossi P, Cortinovis D, Fatigoni S, et al. A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin. Ann Oncol. 2017;28(10):2547-2551. View abstract.
Braga Tibaes JR, Martins LB, Rodrigues AMDS, Amaral MHA, Teixeira AL, Ferreira AVM. Ginger supplementation does not increase energy expenditure in female adults. Nutrition 2022;103-104:111803. View abstract.
Brockwell C, Ampikaipakan S, Sexton DW, Price D, Freeman D, Thomas M, Ali M, Wilson AM. Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2014;9:715-21. View abstract.
Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86. View abstract.
Cady RK, Schreiber CP, Beach ME, et al. Gelstat Migraine (sublingually administered feverfew and ginger compound) for acute treatment of migraine when administered during the mild pain phase. Med Sci Monit. 2005;11:I65-69. View abstract.
Calvert I. Ginger: an essential oil for shortening labour? Pract Midwife. 2005;8:30-4. View abstract.
Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, et al. The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol 2006;194:95-9. View abstract.
Chang WP, Peng YX. Does the Oral Administration of Ginger Reduce Chemotherapy-Induced Nausea and Vomiting?: A Meta-analysis of 10 Randomized Controlled Trials. Cancer Nurs. 2019;42(6):E14-E23. View abstract.
Chiang HM, Chao PD, Hsiu SL, et al. Ginger significantly decreased the oral bioavailability of cyclosporine in rats. Am J Chin Med. 2006;34:845-55. View abstract.
Chitre D, Nadkarni S, Jagtap N, et al. Phase III randomized clinical trial of BV-4051, an Ayurvedic polyherbal formulation in moderate SARS-CoV-2 infections and its impact on inflammatory biomarkers. Phytother Res 2022. View abstract.
Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20. View abstract.
Choi JS, Han JY, Ahn HK, et al. Assessment of fetal and neonatal outcomes in the offspring of women who had been treated with dried ginger (Zingiberis rhizoma siccus) for a variety of illnesses during pregnancy. J Obstet Gynaecol. 2015;35(2):125-30. View abstract.
Chopra A, Saluja M, Tillu G, Sarmukkaddam S, Venugopalan A, Narsimulu G, Handa R, Sumantran V, Raut A, Bichile L, Joshi K, Patwardhan B. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial. Rheumatology (Oxford) 2013;52(8):1408-17. View abstract.
Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. View abstract.
Crichton M, Marshall S, Marx W, McCarthy AL, Isenring E. Efficacy of ginger (Zingiber officinale) in ameliorating chemotherapy-induced nausea and vomiting and chemotherapy-related outcomes: A systematic review update and meta-analysis. J Acad Nutr Diet. 2019;119(12):2055-2068. View abstract.
Dabaghzadeh F, Khalili H, Dashti-Khavidaki S, Abbasian L, Moeinifard A. Ginger for prevention of antiretroviral-induced nausea and vomiting: a randomized clinical trial. Expert Opin Drug Saf 2014;13(7):859-66. View abstract.
Daily JW, Zhang X, Kim da S, et al. Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Pain Med. 2015;16(12):2243-55. View abstract.
Dastgheib M, Barati-Boldaji R, Bahrampour N, et al. A comparison of the effects of cinnamon, ginger, and metformin consumption on metabolic health, anthropometric indices, and sexual hormone levels in women with poly cystic ovary syndrome: A randomized double-blinded placebo-controlled clinical trial. Front Nutr. 2022 Nov 29;9:1071515. View abstract.
Dominguez-Balmaseda D, Diez-Vega I, Larrosa M, et al. Effect of a Blend of Zingiber officinale Roscoe and Bixa orellana L. Herbal Supplement on the Recovery of Delayed-Onset Muscle Soreness Induced by Unaccustomed Eccentric Resistance Training: A Randomized, Triple-Blind, Placebo-Controlled Trial. Front Physiol. 2020;11:826. View abstract.
Drozdov VN, Kim VA, Tkachenko EV, Varvanina GG. Influence of a specific ginger combination on gastropathy conditions in patients with osteoarthritis of the knee or hip. J Alt Compl Med 2012;18:583-8. View abstract.
Eberhart LH, Mayer R, Betz O, et al. Ginger does not prevent postoperative nausea and vomiting after laparoscopic surgery. Anesth Analg 2003;96:995-8. View abstract.
Ebrahimzadeh A, Ebrahimzadeh A, Mirghazanfari SM, Hazrati E, Hadi S, Milajerdi A. The effect of ginger supplementation on metabolic profiles in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2022;65:102802. View abstract.
Emrani Z, Shojaei E, Khalili H. Ginger for Prevention of Antituberculosis-induced Gastrointestinal Adverse Reactions Including Hepatotoxicity: A Randomized Pilot Clinical Trial. Phytother Res. 2016;30(6):1003-9. View abstract.
Ernst E, Pittler MH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br J Anaesth 2000;84:367-71. View abstract.
Feng XG, Hao WJ, Ding Z, et al. Clinical study on tongyan spray for post-stroke dysphagia patients: a randomized controlled trial. Chin J Integr Med. 2012;18:345-9. View abstract.
Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24. View abstract.
Foshati S, Poursadeghfard M, Heidari Z, Amani R. The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind randomized controlled trial. Food Funct 2023;14(8):3701-3711. View abstract.
Foshati S, Poursadeghfard M, Heidari Z, Amani R. The effects of ginger supplementation on common gastrointestinal symptoms in patients with relapsing-remitting multiple sclerosis: a double-blind randomized placebo-controlled trial. BMC Complement Med Ther 2023;23(1):383. View abstract.
Frondoza CG, Sohrabi A, Polotsky A, et al. An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures. In Vitro Cell Dev Biol Anim 2004;40:95-101. View abstract.
Geiger J. The essential oil of ginger, Zingiber officinale, and anaesthesia. Int J Aromather 2005;15:7-14.
Ghayur MN, Gilani AH. Ginger lowers blood pressure through blockade of voltage-dependent calcium channels. J Cardiovasc Pharmacol 2005;45:74-80. View abstract.
Greenway FL, Liu Z, Martin CK, et al. Safety and efficacy of NT, an herbal supplement, in treating human obesity. Int J Obes (Lond). 2006;30:1737-41. View abstract.
Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against seasickness: a controlled trial on the open sea. Acta Otolaryngol 1998;105:45-9. View abstract.
Grontved A, Hentzer E. Vertigo-reducing effect of ginger root. A controlled clinical study. ORL J Otorhinolaryngol Relat Spec 1986;48:282-6. View abstract.
Haghighi M, Khalva A, Toliat T, Jallaei S. Comparing the effects of ginger (Zingiber officinale) extract and ibuprofen on patients with osteoarthritis. Arch Iran Med 2005;8:267-71.
Hajimoosayi F, Jahanian Sadatmahalleh S, Kazemnejad A, Pirjani R. Effect of ginger on the blood glucose level of women with gestational diabetes mellitus (GDM) with impaired glucose tolerance test (GTT): a randomized double-blind placebo-controlled trial. BMC Complement Med Ther. 2020;20(1):116. View abstract.
Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. View abstract.
Heitmann K, Nordeng H, Holst L. Safety of ginger use in pregnancy: results from a large population-based cohort study. Eur J Clin Pharmacol 2012 Jun 17. View abstract.
Higashikawa F, Nakaniida Y, Li H, et al. Beneficial Effects of Ginger Extract on Eye Fatigue and Shoulder Stiffness: A Randomized, Double-Blind, and Placebo-Controlled Parallel Study. Nutrients 2024;16(16):2715. View abstract.
Hirata A, Funato H, Nakai M, et al. Ginger Orally Disintegrating Tablets to Improve Swallowing in Older People. Biol Pharm Bull. 2016;39(7):1107-11. View abstract.
Holtmann S, Clarke AH, Scherer H, et al. The anti-motion sickness mechanism of ginger. A comparative study with placebo and dimenhydrinate. Acta Otolaryngol. 1989;108:168-74. View abstract.
Hu ML, Rayner CK, Wu KL, et al. Effect of ginger on gastric motility and symptoms of functional dyspepsia. World J Gastroenterol. 2011;17:105-10. View abstract.
Hu Y, Amoah AN, Zhang H, et al. Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis. J Matern Fetal Neonatal Med. 2020:1-10. View abstract.
Hunt R, Dienemann J, Norton HJ, Hartley W, Hudgens A, Stern T, Divine G. Aromatherapy as treatment for postoperative nausea: a randomized trial. Anesth Analg 2013;117(3):597-604. View abstract.
Husain I, Dale OR, Idrisi M, et al. Evaluation of the Herb-Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents. J Agric Food Chem. 2023;71(19):7521-7534. View abstract.
Islam MS, Choi H. Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats. J Med Food. 2008;11:152-9. View abstract.
Jatuten N, Piyakunmala P, Budkaew J, Chumworathayi B. Effect of topical Zingiber cassumunar on painful diabetic neuropathy: a double-blind randomized-controlled trial. F1000Res 2023;12:334. View abstract.
Jenabi E. The effect of ginger for relieving of primary dysmenorrhoea. J Pak Med Assoc 2013;63(1):8-10. View abstract.
Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145. View abstract.
Jiang X, Blair EY, McLachlan AJ. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006;46:1370-8. View abstract.
Jiang X, Williams KM, Liauw WS, et al. Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2005;59:425-32. View abstract.
Kalava A, Darji SJ, Kalstein A, Yarmush JM, SchianodiCola J, Weinberg J. Efficacy of ginger on intraoperative and postoperative nausea and vomiting in elective cesarean section patients. Eur J Obstet Gynecol Reprod Biol 2013;169(2):184-8. View abstract.
Kamali A, Beigi S, Shokrpour M, Pazuki S. The efficacy of ginger and doxedetomidine in reducing postoperative nausea and vomiting in patients undergoing abdominal hysterectomy. Altern Ther Health Med. 2020;26(2):28-33. View abstract.
Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. View abstract.
Kashefi F, Khajehei M, Alavinia M, Golmakani E, Asili J. Effect of ginger (Zingiber officinale) on heavy menstrual bleeding: a placebo-controlled, randomized clinical trial. Phytother Res. 2015;29(1):114-9. View abstract.
Kashefi F, Khajehei M, Tabatabaeichehr M, Alavinia M, Asili J. Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial. Pain Manag Nurs. 2014;15(4):826-33. View abstract.
Kazemian A, Toghiani A, Shafiei K, et al. Evaluating the efficacy of mixture of Boswellia carterii, Zingiber officinale, and Achillea millefolium on severity of symptoms, anxiety, and depression in irritable bowel syndrome patients. J Res Med Sci. 2017;22:120. View abstract.
Khodaie L, Sadeghpoor O. Ginger from ancient times to the new outlook. Jundishapur J Nat Pharm Prod 2015;10(1):e18402. View abstract.
Koçak I, Yücepur C, Gökler O. Is Ginger Effective in Reducing Post-tonsillectomy Morbidity? A Prospective Randomised Clinical Trial. Clin Exp Otorhinolaryngol. 2018;11(1):65-70. View abstract.
Konmun J, Danwilai K, Ngamphaiboon N, Sripanidkulchai B, Sookprasert A, Subongkot S. A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy. Med Oncol. 2017;34(4):69. View abstract.
Kotowski U, Kadletz L, Schneider S, et al. 6-shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines. Phytother Res. 2018;32(2):340-347. View abstract.
Kruth P, Brosi E, Fux R, et al. Ginger-associated overanticoagulation by phenprocoumon. Ann Pharmacother 2004;38:257-60. View abstract.
Langner E, Greifenberg S, Gruenwald J. Ginger: history and use. Adv Ther 1998;15:25-44. View abstract.
Leach MJ, Kumar S. The clinical effectiveness of ginger (Zingiber officinale) in adults with osteoarthritis. Int J Evid Based Healthc 2008;6:311-20. View abstract.
Lee J, Oh H. Ginger as an antiemetic modality for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis. Oncol Nurs Forum 2013;40(2):163-70. View abstract.
Lesho EP, Saullo L, Udvari-Nagy S. A 76-year-old woman with erratic anticoagulation. Cleve Clin J Med. 2004;71:651-6. View abstract.
Li X, Qin Y, Liu W, Zhou XY, Li YN, Wang LY. Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial. Integr Cancer Ther. 2018:1534735417753541. View abstract.
Li Y, Yang D, Gao X, et al. Ginger supplement significantly reduced length of hospital stay in individuals with COVID-19. Nutr Metab (Lond). 2022 Dec 28;19(1):84. View abstract.
Lien HC, Sun WM, Chen YH, et al. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection. Am J Physiol Gastrointest Liver Physiol. 2003;284:G481-9. View abstract.
Lopez, H. L., Ziegenfuss, T. N., Hofheins, J. E., Habowski, S. M., Arent, S. M., Weir, J. P., and Ferrando, A. A. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. J Int Soc Sports Nutr 2013;10(1):22. View abstract.
Lua PL, Salihah N, Mazlan N. Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer. Complement Ther Med. 2015;23(3):396-404. View abstract.
Lumb AB. Mechanism of antiemetic effect of ginger. Anaesthesia 1993;48:1118. View abstract.
Maenthaisong R, Chaiyakunapruk N, Tiyaboonchai W, Tawatsin A, Rojanawiwat A, Thavara U. Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions: a randomized controlled trial. Complement Ther Med 2014;22(1):34-9. View abstract.
Young HY, Liao JC, Chang YS, et al. Synergistic effect of ginger and nifedipine on human platelet aggregation: a study in hypertensive patients and normal volunteers. Am J Chin Med. 2006;34:545-51. View abstract.
Yousefi O, Ghazi-Mirsaiid S, Azami P, et al. Effect of a Boswellia and Ginger mixture on the memory dysfunction of the mild traumatic brain injury patients: a randomized, double-blind controlled trial. Bull Emerg Trauma. 2022;10(4):157-64. doi: 10.30476/BEAT.2022.97106.1400. View abstract.
Zahmatkash M, Vafaeenasab MR. Comparing analgesic effects of a topical herbal mixed medicine with salicylate in patients with knee osteoarthritis. Pak J Biol Sci. 2011;14:715-9. View abstract.
Zegota Z, Gozdzik J, Glogowska-Szelag J. Prospective, multicenter evaluation of a polyherbal supplement alongside standard-of-care treatment for mild knee osteoarthritis. Adv Orthop. 2021;2021:5589597. View abstract.
Zhang S, DiMango E, Zhu Y, Saroya TK, Emala CW, Sang S. Pharmacokinetics of Gingerols, Shogaols, and Their Metabolites in Asthma Patients. J Agric Food Chem 2022;70(31):9674-9683. View abstract.
Zhao C, Chen W, Wang D, et al. Ginger (Zingiber officinale Roscoe) preparations for prophylaxis of postoperative nausea and vomiting: A Bayesian network meta-analysis. J Ethnopharmacol 2023;317:116791. View abstract.
Zhu J, Chen H, Song Z, Wang X, Sun Z. Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complement Alt Med 2018. View abstract.
Zick, S. M., Ruffin, M. T., Lee, J., Normolle, D. P., Siden, R., Alrawi, S., and Brenner, D. E. Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting. Support.Care Cancer 2009;17(5):563-572. View abstract.
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