BROMELAIN: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Bromelain is a type of enzyme called a proteolytic enzyme. It is found in pineapple juice and in the pineapple stem.

Bromelain causes the body to make substances that fight pain and swelling. Bromelain also contains chemicals that seem to interfere with tumor cells and slow blood clotting.

People use bromelain for muscle soreness, pain, burns, kidney stones, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse bromelain with other proteolytic enzymes (proteases), such as chymotrypsin, ficin, papain, serrapeptase, or trypsin. These are not the same.

Uses & Effectiveness

We currently have no information for BROMELAIN overview.

Side Effects

When taken by mouth: Bromelain is possibly safe for most people. Doses of up to 240 mg daily have been used safely for up to one year. Bromelain might cause some side effects, including diarrhea and stomach upset.

When applied to the skin: Bromelain is possibly safe. It might cause allergic reactions in some people.

Special Precautions and Warnings

Pregnancy and breast-feeding: There isn't enough reliable information to know if bromelain is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Allergies: People with other allergies might also be allergic to bromelain. Use cautiously if you are allergic to pineapple, latex, ragweed, Echinacea, chrysanthemums, marigolds, daisies, wheat, celery, papain, carrot, fennel, cypress pollen, grass pollen, or other plants.

Surgery: Bromelain might increase the risk of bleeding during and after surgery. Stop using bromelain at least 2 weeks before a scheduled surgery.

Interactions

Moderate Interaction

Be cautious with this combination

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with BROMELAIN
Bromelain might slow blood clotting. Taking bromelain along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Minor Interaction

Be watchful with this combination

Antibiotics (Tetracycline antibiotics) interacts with BROMELAIN
Taking bromelain might increase how much antibiotic the body absorbs. Taking bromelain along with some antibiotics called tetracyclines might increase the effects and side effects of these antibiotics.

Dosing

Bromelain has most often been used by adults in doses of 40-400 mg by mouth daily for up to 13 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

View References

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BROMELAIN - Uses, Side Effects, and More